Hordenine → HCID 69417244, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 45 from methyl 4-((1S)-1-{[(2,5-dichloropyridin-3-yl)carbonyl]amino}ethyl)benzoate (step 1 of Example 48) and 4-[2-(dimethylamino)ethyl]phenol: 1H-NMR (CDCl3) δ 8.53 (1H, d, J=2.6 Hz), 8.23 (1H, d, J=7.5 Hz), 8.13 (1H, d, J=2.8 Hz), 8.02–7.98 (2H, m), 7.43 (2H, d, J=8.3 Hz), 7.33–7.30 (2H, m), 7.11–7.06 (2H, m), 5.39–5.30 (1H, m), 3.90 (3H, s), 2.87–2.82 (2H, m), 2.63–2.58 (2H, m), 2.33 (6H, s), 1.59 (3H, d, J=7.0 Hz).

Provenance & Evidence