(S)-Methyl 4-(1-aminoethyl)benzoate hydrochloride → HCID 69418253, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 3 of Example 1 from 5-chloro-2-[(5-chloropyridin-2-yl)oxy]benzoic acid (step 2) and methyl 4-[(1S)-1-aminoethyl]benzoate hydrochloride (step 3 of Example 5): 1H-NMR (CDCl3) δ 8.04 (1H, d, J=2.6 Hz), 7.94 (1H, d, J=2.6 Hz), 7.91 (2H, d, J=8.3 Hz), 7.63 (1H, dd, J=8.8, 2.6 Hz), 7.43 (1H, dd, J=8.8, 2.6 Hz), 7.22 (2H, d, J=8.3 Hz), 7.18 (1H, d, J=8.0 Hz), 7.00 (1H, d, J=8.8 Hz), 6.80 (1H, d, J=8.8 Hz), 5.28–5.16 (1H, m), 3.91 (3H, s), 1.42 (3H, d, J=7.0 Hz).

Provenance & Evidence