(S)-Methyl 4-(1-aminoethyl)benzoate hydrochloride → HCID 69418636, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 3 of Example 1 from 5-chloro-2-(3-fluorobenzyl)benzoic acid (step 3) and methyl 4-[(1S)-1-aminoethyl]benzoate hydrochloride (step 3 of Example 5): 1H-NMR (CDCl3) δ 8.00–7.96 (2H, m), 7.36–7.14 (6H, m), 6.90–6.74 (3H, m), 5.93 (1H, d, J=7.3 Hz), 5.20 (1H, dq, J=7.3, 7.0 Hz), 4.12 (2H, s), 3.92 (3H, s), 1.44 (3H, d, J=7.0 Hz); MS (ESI) m/z 426 (M+H)+, 424 (M−H)−.

Provenance & Evidence