2,3-Difluorophenol → HCID 69418155, compound

HRID 1293283Notes

Reaction equation

HRID 1293283 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5](F)=[C:6]([CH:11]=1)[C:7]([O:9][CH3:10])=[O:8].[F:13][C:14]1[C:19]([F:20])=[CH:18][CH:17]=[CH:16][C:15]=1[OH:21]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:21][C:15]2[CH:16]=[CH:17][CH:18]=[C:19]([F:20])[C:14]=2[F:13])=[C:6]([CH:11]=1)[C:7]([O:9][CH3:10])=[O:8]

Participants

3

Reactant 2

HCID 808792,3-DifluorophenolHCID 21525433Methyl 5-chloro-2-fluorobenzoate

Product 1

HCID 69418155HCID 69418155, compound

Procedure

The title compound was prepared according to the procedure described in step 1 of Example 67 from methyl 5-chloro-2-fluorobenzoate and 2,3-difluorophenol: 1H-NMR (CDCl3) δ 7.94 (1H, d, J=2.6 Hz), 7.47 (1H, dd, J=8.7, 2.6 Hz), 7.05–6.86 (3H, m), 6.72–6.60 (1H, m), 3.85 (3H, s).

Sources & evidence

ORD record
ord-d52e943046544051bb78131fb7060c58
Source dataset
uspto-grants-2007_07
Patent number
US07238714B2

Reaction notes

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