M-Cresol → HCID 69417403, compound

HRID 1293292Notes

Reaction equation

HRID 1293292 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5](F)=[C:6]([CH:11]=1)[C:7]([O:9][CH3:10])=[O:8].[CH:13]1[C:18]([OH:19])=[CH:17][CH:16]=[CH:15][C:14]=1[CH3:20]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:19][C:18]2[CH:17]=[CH:16][CH:15]=[C:14]([CH3:20])[CH:13]=2)=[C:6]([CH:11]=1)[C:7]([O:9][CH3:10])=[O:8]

Participants

3

Reactant 2

HCID 342M-CresolHCID 21525433Methyl 5-chloro-2-fluorobenzoate

Product 1

HCID 69417403HCID 69417403, compound

Procedure

The title compound was prepared according to the procedure described in step 1 of Example 67 from methyl 5-chloro-2-fluorobenzoate and m-cresol: 1H-NMR (CDCl3) δ 7.89 (1H, d, J=2.8 Hz), 7.40 (1H, dd, J=8.8, 2.8 Hz), 7.21 (1H, t, J=7.9 Hz), 6.96–6.87 (2H, m), 6.81–6.72 (2H, m), 3.83 (3H, s), 2.83 (3H, s).

Sources & evidence

ORD record
ord-f8642e9b5fc04cb9b3e796e12150c9e6
Source dataset
uspto-grants-2007_07
Patent number
US07238714B2

Reaction notes

Loading…