(S)-Methyl 4-(1-aminoethyl)benzoate hydrochloride → HCID 69418250, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 3 of Example 1 from methyl 4-[(1S)-1-aminoethyl]benzoate hydrochloride (step 3 of Example 5) and 5-chloro-2-(2,6-difluorophenoxy)benzoic acid (step 4): 1H-NMR (CDCl3) δ 8.16 (1H, d, J=2.8 Hz), 8.00 (2H, d, J=8.4 Hz), 7.83–7.74 (1H, m), 7.45 (2H, d, J=8.4 Hz), 7.35–7.23 (2H, m), 7.16–7.04 (2H, m), 6.67–6.61 (1H, m), 5.48–5.33 (1H, m), 3.90 (3H, s), 1.59 (3H, d, J=7.0 Hz)); MS (ESI) m/z 446 (M+H)+.

Provenance & Evidence