2,5-Difluorophenol → HCID 69417267, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 45 from tert-butyl 4-((1S)-1-{[(2,5-dichloropyridin-3-yl)carbonyl]amino}ethyl)benzoate (step 1 of Example 45) and 2,5-difluorophenol: 1H-NMR (CDCl3) δ 8.54 (1H, d, J=2.6 Hz), 8.12 (1H, d, J=2.6 Hz), 8.00–7.87 (3H, m), 7.43–7.37 (2H, m), 7.25–7.11 (2H, m), 7.05–6.96 (1H, m), 5.42–5.32 (1H, m), 1.61–1.58 (12H, m); MS (ESI) m/z 489 (M+H)+, 487 (M−H)−.

Provenance & Evidence