2-Chloro-5-fluorophenol → HCID 69417877, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 45 from tert-butyl 4-((1S)-1-{[(2,5-dichloropyridin-3-yl)carbonyl]amino}ethyl)benzoate (step 1 of Example 45) and 2-chloro-5-fluorophenol: 1H-NMR (CDCl3) δ 8.55 (1H, d, J=2.7 Hz), 8.11 (1H, d, J=2.7 Hz), 8.06–8.04 (1H, m), 7.97–7.94 (2H, m), 7.51–7.45 (1H, m), 7.43–7.40 (2H, m), 7.12–7.00 (2H, m), 5.43–5.32 (1H, m), 1.61–1.58 (12H, m); MS (ESI) m/z 505 (M+H)+, 503 (M−H)−.

Provenance & Evidence