3-(Methylsulfanyl)phenol → HCID 69417682, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 45 from tert-butyl 4-((1S)-1-{[(2,5-dichloropyridin-3-yl)carbonyl]amino}ethyl)benzoate (step 1 of Example 45) and 3-(methylthio)phenol (J. Amer. Chem. Soc. 1957, 79, 717): 1H-NMR (CDCl3) δ 8.55 (1H, d, J=2.7 Hz), 8.15 (1H, d, J=2.7 Hz), 8.13–8.10 (1H, m), 7.97–7.94 (2H, m), 7.41–7.34 (3H, m), 7.20–7.16 (1H, m), 7.03–7.01 (1H, m), 6.93–6.89 (1H, m), 5.41–5.31 (1H, m), 2.50 (3H, s), 1.60–1.57 (12H, m); MS (ESI) m/z 499 (M+H)+, 497 (M−H)−.

Provenance & Evidence