4-Fluoro-3-methylphenol → HCID 69418379, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 45 from tert-butyl 4-((1S)-1-{[(2,5-dichloropyridin-3-yl)carbonyl]amino}ethyl)benzoate (step 1 of Example 45) and 4-fluoro-3-methylphenol: 1H-NMR (CDCl3) δ 8.55 (1H, d, J=2.6 Hz), 8.23–8.10 (2H, m), 7.96 (2H, d, J=8.4 Hz), 7.41 (2H, d, J=8.4 Hz), 7.15–6.90 (3H, m), 5.50–5.30 (1H, m), 2.32 (3H, s), 1.65–1.55 (3H, m), 1.58 (9H, s); MS (ESI) m/z 485 (M+H)+, 483 (M−H)−.

Provenance & Evidence