4-Chloro-3-methylphenol → HCID 69418097, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 45 from tert-butyl 4-((1S)-1-{[(2,5-dichloropyridin-3-yl)carbonyl]amino}ethyl)benzoate (step 1 of Example 45) and 4-chloro-3-methylphenol: 1H-NMR (CDCl3) δ 8.54 (1H, d, J=2.6 Hz), 8.15 (1H, d, J=2.6 Hz), 8.09 (1H, d, J=7.3 Hz), 7.95 (2H, d, J=8.3 Hz), 7.47–7.37 (3H, m), 7.03 (1H, d, J=2.8 Hz), 6.96 (1H, dd, J=8.6, 2.8 Hz), 5.36 (1H, dq, J=7.3, 7.0 Hz), 2.41 (3H, s), 1.60 (3H, d, J=7.0 Hz), 1.58 (9H, s); MS (ESI) m/z 501 (M+H)+, 499 (M−H)−.

Provenance & Evidence