4-Chloro-2-methylphenol → HCID 69417757, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 45 from methyl 4-((1S)-1-{[(2,5-dichloropyridin-3-yl)carbonyl]amino}ethyl)benzoate (step 1 of Example 48) and 4-chloro-2-methylphenol: 1H-NMR (CDCl3) δ 8.57 (1H, d, J=2.6 Hz), 8.14 (1H, d, J=7.6 Hz), 8.11 (1H, d, J=2.6 Hz), 8.01 (2H, d, J=8.2 Hz), 7.43 (2H, d, J=8.2 Hz), 7.31 (1H, d, J=2.4 Hz), 7.27 (1H, dd, J=8.6, 2.4 Hz), 7.04 (1H, d, J=8.6 Hz), 5.36 (1H, dq, J=7.6, 7.1 Hz), 3.91 (3H, s), 2.11 (3H, s), 1.60 (3H, d, J=7.1 Hz); MS (ESI) m/z 459 (M+H)+, 457 (M−H)−.

Provenance & Evidence