HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-fluoronicotinic acid → HCID 86760502, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-fluoronicotinic acid | HCID 11435243 | — |
| Reactant | (S)-Methyl 4-(1-aminoethyl)benzoate hydrochloride | HCID 57462942 | — |
| Product | HCID 86760502 | HCID 86760502 | — |
Reaction Steps
The title compound was prepared according to the procedure described in step 1 of Example 45 from 2-chloro-5-fluoronicotinic acid and methyl 4-[(1S)-1-aminoethyl]benzoate hydrochloride (step 3 of Example 5): 1H-NMR (CDCl3) δ 8.54 (1H, d, J=2.9 Hz), 8.05 (2H, d, J=8.4 Hz), 7.92 (1H, dd, J=7.8, 2.9 Hz), 7.47 (2H, d, J=8.4 Hz), 6.91 (1H, m), 5.36 (1H, m), 3.92 (3H, s), 1.64 (3H, d, J=6.9 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07238714B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-92b437d8586d4f558da7d72487ba34cb |
| Source note | uspto-grants-2007_07 |