7-Isoquinolinol → HCID 69416321, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 45 methyl 4-((1S)-1-{[(2,5-dichloropyridin-3-yl)carbonyl]amino}ethyl)benzoate (step 1 of Example 48) and isoquinolin-7-ol: 1H-NMR (CDCl3) δ 9.27 (1H, s), 8.59 (2H, m), 8.13–8.10 (2H, m), 8.00 (2H, d, J=8.4 Hz), 7.94 (1H, d, J=8.9 Hz), 7.74 (2H, m), 7.50 (1H, dd, J=8.9, 2.3 Hz), 7.45 (2H, d, J=8.4 Hz), 5.40 (1H, m), 3.89 (3H, s), 1.61 (3H, d, J=7.0 Hz).

Provenance & Evidence