3-Fluoro-4-methylphenol → HCID 69418056, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 45 methyl 4-((1S)-1-{[(2,5-dichloropyridin-3-yl)carbonyl]amino}ethyl)benzoate (step 1 of Example 48) and 3-fluoro-4-methylphenol: 1H-NMR (CDCl3) δ 8.54 (1H, d, J=2.8 Hz), 8.14 (1H, d, J=2.8 Hz), 8.07 (1H, d, J=7.7 Hz), 8.00 (2H, d, J=8.4 Hz), 7.41 (2H, d, J=8.4 Hz), 7.26 (1H, m), 6.25 (2H, m), 5.36 (1H, m), 3.91 (3H, s), 2.30 (3H, s), 1.59 (3H, d, J=7.0 Hz); MS (ESI) m/z 443 (M+H)+, 441 (M−H)−.

Provenance & Evidence