HCID 66756492, compound → HCID 66756635, compound

HRID 1293346Notes

Reaction equation

HRID 1293346 reaction equation
[CH2:1]([C:3]1[CH2:4][CH2:5][C@@H:6]([C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:7]=1)[CH3:2]>C(O)C.[Pd]>[CH2:1]([C@@H:3]1[NH:7][C@H:6]([C:8]([O:10][CH2:11][CH3:12])=[O:9])[CH2:5][CH2:4]1)[CH3:2]

Participants

4

Reactant 1

HCID 66756492HCID 66756492, compound

Product 1

HCID 66756635HCID 66756635, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Ethyl (2S)-5-ethyl-3,4-dihydro-2H-pyrrole-2-carboxylate dissolved in ethanol (32 mL) was stirred with 0.30 g of 10% Pd/C and under hydrogen (60 psi) for 16 hours. The catalyst was removed by filtration, and the filtrate was concentrated under reduced pressure to provide the titled compound. MS (CI) m/z 172 (M+H)+.

Workup

  1. customThe catalyst was removed by filtration
  2. concentrationthe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-ae9b671689664e3c93145b5ecdb6fddf
Source dataset
uspto-grants-2007_07
Patent number
US07238724B2

Reaction notes

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