HCID 69282516, compound → HCID 69282503, compound

Participants

Reaction Steps

To a solution of methyl-8-chloro-9-cyclohexylmethyl-1-methoxy-9H-4-carbazole carboxylate (95 mg 0.2464 mmoles) in 5 mL methanol, 2 mL of 10% sodium hydroxide solution was added and refluxed for 3 hrs. Methanol from the reaction mixture was evaporated under reduced pressure, diluted with ethyl acetate (50 mL) and washed with 10% sodium hydroxide solution (2×20 mL), this aqueous layer was acidified with 1N HCl and extracted with ethyl acetate (2×25 mL), dried over sodium sulfate and concentrated to give 90 mg of the title compound.

Provenance & Evidence