反应详情

To a suspension of 2,6-dinitrobenzaldehyde (19.6 g, 0.1 mole) in methanol (200 ml), sodium borohydride (5.8 g) was added in a small portion at 15°-25° C. The resultant mixture was stirred at room temperature for 1 hour and then concentrated. To the residue, H2O (100 ml) and chloroform (100 ml) were added, followed by stirring for 1 hour. The chloroform layer was separated, washed with H2O, dried over anhydrous MgSO4 and evaporated to afford 15.0 g of 2,6-dinitrobenzyl alcohol as yellow crystals, m.p. 92.5°-93.5° C.

1. additionwas added in a small portion at 15°-25° C
2. concentrationconcentrated
3. additionTo the residue, H2O (100 ml) and chloroform (100 ml) were added
4. customThe chloroform layer was separated
5. washwashed with H2O
6. dry with materialdried over anhydrous MgSO4
7. customevaporated