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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1293799Generated: October 30, 2026

HCID 61052832, compound → HCID 86608042, compound

https://huagongshe.com/reaction/1293799

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 61052832HCID 61052832—
Reactant3-Ethynyl-7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidineHCID 71539732—
ProductHCID 86608042HCID 86608042—

Reaction Steps

The title compound was prepared from 3-ethynyl-7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine (example C.1) (355 mg, 1.0 mmol) and 2-Chloro-4-methyl-thiazole-5-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide (example B.22) (256 mg, 1.0 mmol) according to general procedure II. Obtained as a yellow solid (190 mg, 32%). MS (ISP) 604.0[(M+H)+]; mp 216–218° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07238808B2
Source datasetuspto-grants-2007_07
ORD IDord-2557e4ddeaeb4013bd9b1eab89dbc576
Source noteuspto-grants-2007_07