HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2,4-difluoro-N-(2-hydroxyethyl)benzenesulfonamide → HCID 86608075, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2,4-difluoro-N-(2-hydroxyethyl)benzenesulfonamide | HCID 67000352 | — |
| Reactant | 3-Ethynyl-7-difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine | HCID 86608034 | — |
| Product | HCID 86608075 | HCID 86608075 | — |
Reaction Steps
The title compound was prepared from 7-Difluoromethyl-3-ethynyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine (example C.2) (337 mg, 1.0 mmol) and 5-bromo-2,4-difluoro-N-(2-hydroxy-ethyl)-benzenesulfonamide (example B.37) (411 mg, 1.0 mmol) according to general procedure II. Obtained as a yellow solid (100 mg, 17%). MS (ISP) 573.1 [(M+H)+]; mp 149–150° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07238808B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-e08354b4553b4a1dbc5ae918a3536a88 |
| Source note | uspto-grants-2007_07 |