Ibuprofen, (+-)- → HCID 15948295, compound

HRID 1294405Notes

Reaction equation

HRID 1294405 reaction equation
[OH:1][C:2]([CH:4]([C:6]1[CH:15]=[CH:14][C:9]([CH2:10][CH:11]([CH3:13])[CH3:12])=[CH:8][CH:7]=1)[CH3:5])=[O:3].[OH-].[Na+].O.O.O.O.O.O.[Cl-].[Sr+2:25].[Cl-]>O>[O-:3][C:2]([CH:4]([C:6]1[CH:7]=[CH:8][C:9]([CH2:10][CH:11]([CH3:12])[CH3:13])=[CH:14][CH:15]=1)[CH3:5])=[O:1].[Sr+2:25].[O-:3][C:2]([CH:4]([C:6]1[CH:7]=[CH:8][C:9]([CH2:10][CH:11]([CH3:12])[CH3:13])=[CH:14][CH:15]=1)[CH3:5])=[O:1]

Participants

5

Reactant 3

HCID 3672Ibuprofen, (+-)-HCID 14798Sodium HydroxideHCID 610186810025-70-4

Product 1

HCID 15948295HCID 15948295, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

Ibuprofen (2.59 g, 12.5 mmol) was dissolved in water (100 ml) containing sodium hydroxide (0.503 g, 12.5 mmol). A solution of strontium chloride hexahydrate (1.68 g, 6.3 mmol) in water (5 ml) was added. The mixture was stirred for 10 minutes at room temperature and the title compound was isolated by filtration and dried. Yield 1.30 g (44%). Melting point >300° C.

Sources & evidence

ORD record
ord-17ef2aaa02194c228bbb1d1cb414ffa2
Source dataset
uspto-grants-2007_07
Patent number
US07241460B2

Reaction notes

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