2-Chloro-4-(trifluoromethyl)pyrimidine → HCID 11772878, compound

HRID 1294484Notes

Reaction equation

HRID 1294484 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:6][CH:7]=1.Cl[C:17]1[N:22]=[C:21]([C:23]([F:26])([F:25])[F:24])[CH:20]=[CH:19][N:18]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[N:13]([C:17]3[N:22]=[C:21]([C:23]([F:26])([F:25])[F:24])[CH:20]=[CH:19][N:18]=3)[CH:14]=2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 27739122-Chloro-4-(trifluoromethyl)pyrimidineHCID 178432693HCID 178432693, compound

Product 1

HCID 11772878HCID 11772878, compound

Procedure

The title compound, MS: m/e=363.1 (M+H+), was prepared in accordance with the general method of example 1 from 4-(3-chloro-phenylethynyl)-2-methyl-1H-imidazole and 2-chloro-4-(trifluoromethyl)pyrimidine.

Sources & evidence

ORD record
ord-8924e404bffd493b8e70da5e7293ed86
Source dataset
uspto-grants-2007_07
Patent number
US07241760B2

Reaction notes

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