2-Fluoro-6-(trifluoromethyl)pyridine → HCID 11256660, compound
Reaction equation
[CH3:1][C:2]1[NH:3][CH:4]=[C:5]([C:7]#[C:8][C:9]2[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=2)[C:12]#[N:13])[N:6]=1.F[C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([C:24]([F:27])([F:26])[F:25])[N:19]=1>>[CH3:1][C:2]1[N:3]([C:18]2[CH:23]=[CH:22][CH:21]=[C:20]([C:24]([F:27])([F:26])[F:25])[N:19]=2)[CH:4]=[C:5]([C:7]#[C:8][C:9]2[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=2)[C:12]#[N:13])[N:6]=1Participants
3
Procedure
The title compound, MS: m/e=353.1 (M+H+), was prepared in accordance with the general method of example 1 from 3-(2-methyl-1H-imidazol-4-ylethynyl)-benzonitrile and 2-fluoro-6-trifluoromethylpyridine.
Sources & evidence
- ORD record
- ord-0a49dd6c41664278a69aaf963dc434cd
- Source dataset
- uspto-grants-2007_07
- Patent number
- US07241760B2
Reaction notes
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