2-Fluoro-4-methylpyridine → 3-[2-Methyl-1-(4-methyl-pyridin-2-yl)-1H-imidazol-4-ylethynyl]-benzonitrile

HRID 1294488Notes

Reaction equation

HRID 1294488 reaction equation
[CH3:1][C:2]1[NH:3][CH:4]=[C:5]([C:7]#[C:8][C:9]2[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=2)[C:12]#[N:13])[N:6]=1.F[C:18]1[CH:23]=[C:22]([CH3:24])[CH:21]=[CH:20][N:19]=1>>[CH3:1][C:2]1[N:3]([C:18]2[CH:23]=[C:22]([CH3:24])[CH:21]=[CH:20][N:19]=2)[CH:4]=[C:5]([C:7]#[C:8][C:9]2[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=2)[C:12]#[N:13])[N:6]=1

Participants

3

Reactant 2

HCID 27374032-Fluoro-4-methylpyridineHCID 178432699HCID 178432699, compound

Product 1

HCID 111856053-[2-Methyl-1-(4-methyl-pyridin-2-yl)-1H-imidazol-4-ylethynyl]-benzonitrile

Procedure

The title compound, MS: m/e=299.2 (M+H+), was prepared in accordance with the general method of example 1 from 3-(2-methyl-1H-imidazol-4-ylethynyl)-benzonitrile and 2-fluoro-4-methylpyridine.

Sources & evidence

ORD record
ord-4f6e742f1b0842d799a9513bedf1610c
Source dataset
uspto-grants-2007_07
Patent number
US07241760B2

Reaction notes

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