2-Chloro-5-fluoropyrimidine → HCID 11335964, compound

HRID 1294493Notes

Reaction equation

HRID 1294493 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:6][CH:7]=1.Cl[C:17]1[N:22]=[CH:21][C:20]([F:23])=[CH:19][N:18]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[N:13]([C:17]3[N:22]=[CH:21][C:20]([F:23])=[CH:19][N:18]=3)[CH:14]=2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 5834662-Chloro-5-fluoropyrimidineHCID 178432693HCID 178432693, compound

Product 1

HCID 11335964HCID 11335964, compound

Procedure

The title compound, MS: m/e=313.1 (M+H+), was prepared in accordance with the general method of example 1 from 4-(3-chloro-phenylethynyl)-2-methyl-1H-imidazole and 2-chloro-5-fluoro-pyrimidine.

Sources & evidence

ORD record
ord-8c0144231df64658abe1e7cd7e50a6f8
Source dataset
uspto-grants-2007_07
Patent number
US07241760B2

Reaction notes

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