3-Chloro-6-methylpyridazine → 3-[4-(3-Chloro-phenylethynyl)-2-methyl-imidazol-1-yl]-6-methyl-pyridazine
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:6][CH:7]=1.Cl[C:17]1[N:18]=[N:19][C:20]([CH3:23])=[CH:21][CH:22]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[N:13]([C:17]3[N:18]=[N:19][C:20]([CH3:23])=[CH:21][CH:22]=3)[CH:14]=2)[CH:5]=[CH:6][CH:7]=1Participants
3
Procedure
The title compound, MS: m/e=309.3 (M+H+), was prepared in accordance with the general method of example 1 from 4-(3-chloro-phenylethynyl)-2-methyl-1H-imidazole and 3-chloro-6-methyl-pyridazine.
Sources & evidence
- ORD record
- ord-2bb0da60c8254a4ca7aa4515630bed09
- Source dataset
- uspto-grants-2007_07
- Patent number
- US07241760B2
Reaction notes
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