2-Fluoro-5-methylpyridine → 2-[4-(3-Chloro-phenylethynyl)-2-methyl-imidazol-1-yl]-5-methyl-pyridine

HRID 1294511Notes

Reaction equation

HRID 1294511 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:6][CH:7]=1.F[C:17]1[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][N:18]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[N:13]([C:17]3[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][N:18]=3)[CH:14]=2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 27746352-Fluoro-5-methylpyridineHCID 178432693HCID 178432693, compound

Product 1

HCID 112437432-[4-(3-Chloro-phenylethynyl)-2-methyl-imidazol-1-yl]-5-methyl-pyridine

Procedure

The title compound, MS: m/e=308.2 (M+), was prepared in accordance with the general method of example 1 from 4-(3-chloro-phenylethynyl)-2-methyl-1H-imidazole and 2-fluoro-5-methylpyridine.

Sources & evidence

ORD record
ord-2ac81e7330d14437b395c3d2bb21db3e
Source dataset
uspto-grants-2007_07
Patent number
US07241760B2

Reaction notes

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