2-Chloro-5-fluoropyridine → HCID 86595395, compound

HRID 1294514Notes

Reaction equation

HRID 1294514 reaction equation
[CH3:1][C:2]1[NH:3][CH:4]=[C:5]([C:7]#[C:8][C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([C:15]([F:18])([F:17])[F:16])[CH:10]=2)[N:6]=1.[Cl:19][C:20]1[CH:25]=[CH:24][C:23](F)=[CH:22][N:21]=1>>[Cl:19][C:20]1[CH:25]=[CH:24][C:23]([N:3]2[CH:4]=[C:5]([C:7]#[C:8][C:9]3[CH:14]=[CH:13][CH:12]=[C:11]([C:15]([F:18])([F:16])[F:17])[CH:10]=3)[N:6]=[C:2]2[CH3:1])=[CH:22][N:21]=1

Participants

3

Reactant 2

HCID 27828012-Chloro-5-fluoropyridineHCID 178432691HCID 178432691, compound

Product 1

HCID 86595395HCID 86595395, compound

Procedure

The title compound, MS: m/e=362.3 (M+), was prepared in accordance with the general method of example 1 from 2-methyl-4-(3-trifluoromethyl-phenylethynyl)-1H-imidazole and 2-chloro-5-fluoro-pyridine.

Sources & evidence

ORD record
ord-1feede6c1d9147f4a284649bafcaedea
Source dataset
uspto-grants-2007_07
Patent number
US07241760B2

Reaction notes

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