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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1294519Generated: October 26, 2026

Dimethylamine, hydrochloride → 3-[1-(5-Dimethylamino-pyridin-3-yl)-2-methyl-1H-imidazol-4-ylethynyl]-benzonitrile

https://huagongshe.com/reaction/1294519

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamine, hydrochlorideHCID 10473—
Reactant3-[1-(5-Fluoro-pyridin-3-yl)-2-methyl-1H-imidazol-4-ylethynyl]-benzonitrileHCID 66879288—
Product3-[1-(5-Dimethylamino-pyridin-3-yl)-2-methyl-1H-imidazol-4-ylethynyl]-benzonitrileHCID 69491666—

Reaction Steps

The title compound, MS: m/e=328.4 (M+), was prepared in accordance with the general method of example 27 from 3-[1-(5-fluoro-pyridin-3-yl)-2-methyl-1H-imidazol-4-ylethynyl]-benzonitrile and dimethylamine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07241760B2
Source datasetuspto-grants-2007_07
ORD IDord-b2ed5ff836664658b102f6cb0d37ccfe
Source noteuspto-grants-2007_07