Thiomorpholine → HCID 11165348, compound

HRID 1294520Notes

Reaction equation

HRID 1294520 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:22])[N:13]([C:15]3[CH:20]=[CH:19][CH:18]=[C:17](F)[N:16]=3)[CH:14]=2)[CH:5]=[CH:6][CH:7]=1.[NH:23]1[CH2:28][CH2:27][S:26][CH2:25][CH2:24]1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:22])[N:13]([C:15]3[N:16]=[C:17]([N:23]4[CH2:28][CH2:27][S:26][CH2:25][CH2:24]4)[CH:18]=[CH:19][CH:20]=3)[CH:14]=2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 67164ThiomorpholineHCID 589062992-[4-[2-(3-Chlorophenyl)ethynyl]-2-methyl-1H-imidazol-1-yl]-6-fluoropyridine

Product 1

HCID 11165348HCID 11165348, compound

Procedure

The title compound, MS: m/e=395.1, 397.1 (M+H+), was prepared in accordance with the general method of example 27 from 2-[4-(3-chloro-phenylethynyl)-2-methylimidazol-1-yl]-6-fluoro-pyridine and thiomorpholine.

Sources & evidence

ORD record
ord-817a283d94a4480ea1deceddfdb69838
Source dataset
uspto-grants-2007_07
Patent number
US07241760B2

Reaction notes

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