Reaction Steps
Synthesized using COMPOUND 68 and the method described for COMPOUND 69. Purity (HPLC): >99%; Optical purity (Chiral HPLC): >99%; (400 MHz, CD3OD) 0.39-0.44 (m, 2H), 0.72-0.78 (m, 2H), 1.04-1.10 (m, 1H), 1.07-1.11 (m, 3H), 1.22 (t, J=6.99 Hz, 3H), 2.20-2.36 (m, 2H), 2.91-3.08 (m, 2H), 3.04 (d, J=7.49 Hz, 2H), 3.06-3.19 (m, 2H), 3.21-3.30 (m, 2H), 3.46-3.60 (m, 4H), 4.33 (s, 1H), 4.52 (s, 2H), 6.62 (dd, J=8.00, 2.44 Hz, 1H), 6.77 (d, J=7.58 Hz, 1H), 6.83 (t, J=1.81 Hz, 1H), 6.94 (dd, J=5.04, 3.53 Hz, 1H), 6.98-7.00 (m, 1H), 7.07 (t, J=7.80 Hz, 1H), 7.25 (dd, J=5.00, 122 Hz, 1H), 7.30 (d, J=8.17 Hz, 2H), 7.50 (d, J=8.16 Hz, 2H). Found. C, 53.58; H, 5.46; N, 7.10. C31H40N4OS×0.70H2O 2.4CF3COOH has C, 53.55; H, 5.50; N, 6.98%. [a]D20=−19.74 deg [c 0.947, MeOH]
