HCID 9983548, compound → HCID 10254423, compound

Participants

Reaction Steps

Synthesized using COMPOUND 27 (250 mg; 0.56 mmol) and the method described for COMPOUND 72. Obtained 163 g; 61% yield. Purity (HPLC-215 nm): >99%; Optical purity (Chiral HPLC-215 nm): >99%. 1H NMR (400 MHz, CD3OD) δ 0.80 (m, 1H), 1.19 (br s, 11H), 1.59 (m, 2H), 1.88 (br s, 5H), 3.14 (br s, 11H), 3.50 (br s, 4H), 4.11 (m, 1H), 7.31 (br s, 3H), 7.67 (br s, 5H). Found: C, 53.63; H, 7.55; N, 8.05. C30H44N4O×5.0HCl×0.7H2O has C, 53.65; H, 7.56; N, 8.34%. [α]D16=+12.7 deg [c 0.50, MeOH].

Provenance & Evidence