HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Isopropoxy-5-methylsulfonylbenzoic acid → (4-Benzoxazol-2-yl-piperazin-1-yl)-(2-isopropoxy-5-methanesulfonyl-phenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Isopropoxy-5-methylsulfonylbenzoic acid | HCID 21100237 | — |
| Reactant | 2-(Piperazin-1-yl)benzo[d]oxazole hydrochloride | HCID 66570214 | — |
| Product | (4-Benzoxazol-2-yl-piperazin-1-yl)-(2-isopropoxy-5-methanesulfonyl-phenyl)-methanone | HCID 58906314 | — |
Reaction Steps
Prepared in analogy to example 1.1 b) from 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example 2.2) and 2-piperazin-1-yl-benzoxazole hydrochloride. The crude material was triturated with diethyl ether to yield the title compound as a colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241761B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-0345cc35c7d1483ead7719dfae3aa076 |
| Source note | uspto-grants-2007_07 |