HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → (2-Isobutoxy-5-methanesulfonyl-phenyl)-[4-(2-methyl-benzothiazol-5-yl)-piperazin-1-yl]-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 2-Isobutoxy-5-methanesulfonyl-benzoic acid | HCID 23503110 | — |
| Reactant | 2-Methyl-5-piperazin-1-yl-benzothiazole hydrochloride | HCID 68895955 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | (2-Isobutoxy-5-methanesulfonyl-phenyl)-[4-(2-methyl-benzothiazol-5-yl)-piperazin-1-yl]-methanone | HCID 11677518 | — |
Reaction Steps
Prepared in analogy to example 1.1 (b) from 2-methyl-5-piperazin-1-yl-benzothiazole hydrochloride and 2-isobutoxy-5-methanesulfonyl-benzoic acid (example 2.4) in acetonitrile. Chromatography (SiO2; ethyl acetate) yields the title compound as a brownish solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241761B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-6820b1783ab146b1942036b9ba4d8468 |
| Source note | uspto-grants-2007_07 |