HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl piperazine-1-carboxylate → Tert-butyl 4-(6-chloroquinolin-2-yl)piperazine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| Reactant | 2,6-Dichloroquinoline | HCID 607502 | — |
| Product | Tert-butyl 4-(6-chloroquinolin-2-yl)piperazine-1-carboxylate | HCID 58906309 | — |
Reaction Steps
Prepared in analogy to example 1.18 (a) from 2,6-dichloroquinoline and piperazine-1-carboxylic acid tert-butyl ester. Crystallisation from methanol yields the title compound as a colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241761B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-ba7ccf07eef04ce0810f0354193f9ad9 |
| Source note | uspto-grants-2007_07 |