HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → (2-Isopropoxy-5-methanesulfonyl-phenyl)-(4-quinoxalin-2-yl-piperazin-1-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 2-Piperazin-1-yl-quinoxaline hydrochloride | HCID 12686416 | — |
| Reactant | 2-Isopropoxy-5-methylsulfonylbenzoic acid | HCID 21100237 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | (2-Isopropoxy-5-methanesulfonyl-phenyl)-(4-quinoxalin-2-yl-piperazin-1-yl)-methanone | HCID 11568709 | — |
Reaction Steps
Prepared in analogy to example 1.1 (b) from 2-piperazin-1-yl-quinoxaline hydrochloride and 2-isopropoxy-5-methanesulfonyl-benzoic acid (example 2.2) in acetonitrile. Chromatography (SiO2; ethyl acetate) yields the title compound as a yellowish foam.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241761B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-3a9cf3cb3a8846f1bcb39119a79c3ece |
| Source note | uspto-grants-2007_07 |