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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1294825Generated: October 26, 2026

3-Isoxazolamine → 1-(5-tert-Butyl-isoxazol-3-ylcarbamoyl)-propyl-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/1294825

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-IsoxazolamineHCID 1810216—
Reactant[1-(5-Tert-butyl-isoxazol-3-ylcarbamoyl)butyl]-carbamic acid tert-butyl esterHCID 69419406—
Product1-(5-tert-Butyl-isoxazol-3-ylcarbamoyl)-propyl-carbamic acid tert-butyl esterHCID 69424122—

Reaction Steps

Prepared by the analogous method for the preparation of [1-(5-tert-butyl-isoxazol-3-ylcarbamoyl)butyl]-carbamic acid tert-butyl ester, starting with an appropriate amino-isoxazole (1 a-b) together with an appropriate N-t-BOC-amino acid methyl or ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07241786B2
Source datasetuspto-grants-2007_07
ORD IDord-d7f47e78ef3147b1bb761a63a2b37375
Source noteuspto-grants-2007_07