HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1294833Generated: October 30, 2026
Potassium Carbonate → (4-Cyclopentyloxyphenyl)(2,2-diethoxyethyl)amine
https://huagongshe.com/reaction/1294833
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Ethane, 2-bromo-1,1-diethoxy- | HCID 74852 | — |
| Reactant | 4-(cyclopentyloxy)aniline | HCID 6484448 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | (4-Cyclopentyloxyphenyl)(2,2-diethoxyethyl)amine | HCID 69151237 | — |
Reaction Steps
A suspension of 4-cyclopentyloxyaniline (8.86 g), bromoacetaldehyde diethyl acetal (13 g), potassium carbonate (13.8 g) and dimethylformamide (100 ml) was heated at 80° C. for 6 hours. Cooling was followed by filtration and concentration of the filtrate. The residue was purified by chromatography on silica gel (eluent: heptane/ethyl acetate 2:1). The product with the molecular weight of 293.41 (C17H27NO3) was obtained in this way; MS (ESI): 294 ([M+H]+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07241787B2 |
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| Source dataset | uspto-grants-2007_07 |
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| ORD ID | ord-1949758c92ec476bae1d3a8c2e7039d5 |
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| Source note | uspto-grants-2007_07 |
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