HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzamide, 2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)- → (2,4-Dimethoxyphenyl)[2-fluoro-3-(trifluoromethyl)phenyl]methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzamide, 2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)- | HCID 11196047 | — |
| Reactant | HCID 178491918 | HCID 178491918 | — |
| Product | (2,4-Dimethoxyphenyl)[2-fluoro-3-(trifluoromethyl)phenyl]methanone | HCID 67021176 | — |
Reaction Steps
Prepared according to Method A step B from 2-fluoro-3-trifluoromethyl-N-methoxy-N-methylbenzamide (4.42 g, 17.6 mmol) and 2,4-dimethoxyphenylmagnesium bromide (32 mL, 0.5 M in THF) to give 1.67 g of the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241791B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-ebf767f84c124dd0bbb8d4dca5b9a741 |
| Source note | uspto-grants-2007_07 |