HCID 86594062, compound → HCID 68883322, compound

HRID 1294874Notes

Reaction equation

HRID 1294874 reaction equation
[F:1][CH:2]1[C:13]([Br:15])(C)[CH:12]=[CH:11][CH:10]=[C:3]1[C:4](N(OC)C)=[O:5].[CH3:16][O:17][C:18]1[CH:23]=[CH:22][C:21]([Mg]Br)=[CH:20][CH:19]=1>>[Br:15][C:13]1[C:2]([F:1])=[C:3]([C:4]([C:21]2[CH:22]=[CH:23][C:18]([O:17][CH3:16])=[CH:19][CH:20]=2)=[O:5])[CH:10]=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 86594062HCID 86594062, compoundHCID 178491912HCID 178491912, compound

Product 1

HCID 68883322HCID 68883322, compound

Procedure

Prepared according to Method A step B from 2-fluoro-3-bromo-N-methoxy-N,3-dimethyl-benzamide (8.00 g, 30.5 mmol) and 4-methoxyphenylmagnesium bromide (65 mL, 0.5 M in THF) to give 3.12 g of the title compound as a white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-22c4d15c163d4ea89a43c7f868b6ff86
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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