2,2',4,4'-Tetrahydroxybenzophenone → 680610-84-8

HRID 1294883Notes

Reaction equation

HRID 1294883 reaction equation
O[C:2]1[CH:17]=[C:16]([OH:18])[CH:15]=[CH:14][C:3]=1[C:4]([C:6]1[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][C:7]=1[OH:13])=O.C([O-])(=O)C.[Na+].Cl.[F:25][C:26]1[CH:31]=[CH:30][C:29]([F:32])=[CH:28][C:27]=1[NH:33][NH2:34]>>[F:25][C:26]1[CH:31]=[CH:30][C:29]([F:32])=[CH:28][C:27]=1[N:33]1[C:2]2[C:3](=[CH:14][CH:15]=[C:16]([OH:18])[CH:17]=2)[C:4]([C:6]2[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][C:7]=2[OH:13])=[N:34]1

Participants

4

Reactant 3

HCID 85712,2',4,4'-TetrahydroxybenzophenoneHCID 517045Sodium AcetateHCID 24720967(2,5-Difluorophenyl)hydrazine--hydrogen chloride (1/1)

Product 1

HCID 135540483680610-84-8Yield 18.9%

Procedure

Prepared according to Method B from 2,2′,4,4′-tetrahydroxybenzophenone (0.4 g, 1.6 mmol), sodium acetate (0.27 g, 3 mmol) and 2,5-difluorophenylhydrazine hydrochloride (0.45 g, 3 mmol) to give 0.107 g of product as an off-white colored solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-aa0603e4ed8f458b9dd5b5b3fdbfe1b2
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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