Cyclohexene → 4-(7-methyl-1-pentyl-1H-indazol-3-yl)phenol

HRID 1294917Notes

Reaction equation

HRID 1294917 reaction equation
C[O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:17]3[C:12](=[C:13]([CH3:18])[CH:14]=[CH:15][CH:16]=3)[N:11]([CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[N:10]=2)=[CH:5][CH:4]=1.B(Br)(Br)Br.C1CCCCC=1>>[CH3:18][C:13]1[CH:14]=[CH:15][CH:16]=[C:17]2[C:12]=1[N:11]([CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[N:10]=[C:9]2[C:6]1[CH:7]=[CH:8][C:3]([OH:2])=[CH:4][CH:5]=1

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 688833953-(4-methoxyphenyl)-7-methyl-1-pentyl-1H-indazole

Product 1

HCID 1363584394-(7-methyl-1-pentyl-1H-indazol-3-yl)phenolYield 43%

Procedure

Prepared according to Method D step C from 3-(4-methoxyphenyl)-7-methyl-1-pentyl-1H-indazole (0.105 g, 0.34 mmol), boron tribromide (0.094 mL, 1.0 mmol) and 0.3 mL of cyclohexene to give the product (0.043 g) as an off-white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-1c7d7ac288e14608af92ac4f5c478b81
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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