Cyclohexene → 4-[7-methyl-2-pentyl-2H-indazol-3-yl]phenol

HRID 1294919Notes

Reaction equation

HRID 1294919 reaction equation
C[O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:10]([CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[N:11]=[C:12]3[C:17]=2[CH:16]=[CH:15][CH:14]=[C:13]3[CH3:18])=[CH:5][CH:4]=1.B(Br)(Br)Br.C1CCCCC=1>>[CH3:18][C:13]1[C:12]2[C:17](=[C:9]([C:6]3[CH:7]=[CH:8][C:3]([OH:2])=[CH:4][CH:5]=3)[N:10]([CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[N:11]=2)[CH:16]=[CH:15][CH:14]=1

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 688820493-(4-methoxyphenyl)-7-methyl-2-pentyl-2H-indazole

Product 1

HCID 1363584404-[7-methyl-2-pentyl-2H-indazol-3-yl]phenolYield 45.3%

Procedure

Prepared according to Method D step C from 3-(4-methoxyphenyl)-7-methyl-2-pentyl-2H-indazole (0.014 g, 0.045 mmol), boron tribromide (0.050 mL, 1.0 mmol) and 0.2 mL of cyclohexene to give the product (0.006 g).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-3653798bd169413ea6c7435c5b90611b
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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