HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropyl iodide → 7-chloro-1-isopropyl-3-(4-methoxyphenyl)-1H-indazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropyl iodide | HCID 6362 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 178489137 | HCID 178489137 | — |
| Product | 7-chloro-1-isopropyl-3-(4-methoxyphenyl)-1H-indazole | HCID 68884368 | 28.6% |
Reaction Steps
Prepared according to Method D step B from 7-chloro-3-(4-methoxyphenyl)-1H-indazole (0.129 g, 0.5 mmol), sodium hydride (60% in oil, 0.024 g, 0.6 mmol) and 2-iodopropane (0.10 mL, 1.0 mmol) to give the title compound (0.043 g) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241791B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-4dc22d516a5641cfbcc3fa1f0ad66fef |
| Source note | uspto-grants-2007_07 |