Cyclohexene → HCID 135543623, compound

HRID 1294939Notes

Reaction equation

HRID 1294939 reaction equation
C[O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:17]3[C:12](=[C:13]([C:18]([F:21])([F:20])[F:19])[CH:14]=[CH:15][CH:16]=3)[N:11]([CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])[N:10]=2)=[CH:5][CH:4]=1.B(Br)(Br)Br.C1CCCCC=1>>[CH2:22]([N:11]1[C:12]2[C:17](=[CH:16][CH:15]=[CH:14][C:13]=2[C:18]([F:21])([F:20])[F:19])[C:9]([C:6]2[CH:7]=[CH:8][C:3]([OH:2])=[CH:4][CH:5]=2)=[N:10]1)[CH2:23][CH2:24][CH2:25][CH3:26]

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 68882051HCID 68882051, compound

Product 1

HCID 135543623HCID 135543623, compoundYield 48.3%

Procedure

Prepared according to Method D step C from 3-(4-methoxyphenyl)-1-pentyl-7-trifluoromethyl-1H-indazole (0.068 g, 0.19 mmol), boron tribromide (0.094 mL, 1.0 mmol) and 0.3 mL of cyclohexene to give the product (0.032 g) as an off-white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-57a88443714345bdab5efa947700d7a4
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

Loading…