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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 129494Generated: October 29, 2026

Piperidin-4-ol → HCID 14994956, compound

https://huagongshe.com/reaction/129494

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidin-4-olHCID 79341—
ReactantHCID 86746987HCID 86746987—
ProductHCID 14994956HCID 1499495698.1%

Reaction Steps

50 g of 1-cyano-1-methylethylphenyl carbonate and 25 g of 4-hydroxypiperidine were heated at 130° C. After completion of the reaction, the resulting product was purified by silica gel column chromatography (elution solvent: hexane:ethyl acetate=1:1-1:2-0:1), thereby obtaining 50.5 g of the intended compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05468740
Source datasetuspto-grants-1995_11
ORD IDord-4caad6a9677c4dadb344db1773c3a3a7
Source noteuspto-grants-1995_11