HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → 3-(4-methoxyphenyl)-1-propyl-7-trifluoromethyl-1H-indazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 1-Iodopropane | HCID 33643 | — |
| Reactant | HCID 178489134 | HCID 178489134 | — |
| Product | 3-(4-methoxyphenyl)-1-propyl-7-trifluoromethyl-1H-indazole | HCID 68882292 | 34.7% |
Reaction Steps
Prepared according to Method D step B from 3-(4-methoxyphenyl)-7-trifluoromethyl-1H-indazole (0.146 g, 0.5 mmol), sodium hydride (60% in oil, 0.024 g, 0.6 mmol) and 1-iodopropane (0.098 mL, 1.0 mmol) to give the title compound (0.058 g) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241791B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-38df4dd17eed4578b144fbd61265c1c5 |
| Source note | uspto-grants-2007_07 |