HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexene → 4-[1-isopropyl-7-(trifluoromethyl)-1H-indazol-3-yl]phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexene | HCID 8079 | — |
| Reactant | Boron tribromide | HCID 25134 | — |
| Reactant | 3-(4-methoxyphenyl)-1-isopropyl-7-trifluoromethyl-1H-indazole | HCID 68883812 | — |
| Product | 4-[1-isopropyl-7-(trifluoromethyl)-1H-indazol-3-yl]phenol | HCID 135428120 | 76.8% |
Reaction Steps
Prepared according to Method D step C from 3-(4-methoxyphenyl)-1-isopropyl-7-trifluoromethyl-1H-indazole (0.043 g, 0.13 mmol), boron tribromide (0.094 mL, 1.0 mmol) and 0.3 mL of cyclohexene to give the product (0.032 g) as an off-white solid, mp 156–157° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241791B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-94f5f067bfe14e77a4d1d228e3d50043 |
| Source note | uspto-grants-2007_07 |