Cyclohexene → HCID 68882253, compound

HRID 1294951Notes

Reaction equation

HRID 1294951 reaction equation
[CH2:1]([N:4]1[C:12]([C:13]2[CH:18]=[CH:17][C:16]([O:19]C)=[CH:15][CH:14]=2)=[C:11]2[C:6]([C:7]([F:22])=[CH:8][CH:9]=[C:10]2C)=[N:5]1)[CH2:2][CH3:3].B(Br)(Br)Br.C1CCCCC=1>>[F:22][C:7]1[CH:8]=[CH:9][CH:10]=[C:11]2[C:6]=1[NH:5][N:4]([CH2:1][CH2:2][CH3:3])[CH:12]2[C:13]1[CH:14]=[CH:15][C:16]([OH:19])=[CH:17][CH:18]=1

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 68884108HCID 68884108, compound

Product 1

HCID 68882253HCID 68882253, compoundYield 10.5%

Procedure

Prepared according to Method D step C from 2-propyl-7-fluoro-3-(4-methoxyphenyl)-methyl-2H-indazole (0.006 g, 0.021 mmol), boron tribromide (0.05 mL, 0.5 mmol) and 0.2 mL of cyclohexene to give the product (0.0006 g).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-8c55e8e1b5064b62b2359aabcb83ea75
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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