Cyclohexene → HCID 136358442, compound

HRID 1294953Notes

Reaction equation

HRID 1294953 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5](C)=[C:6]2[C:10]=1[N:9]([CH:11]([CH3:13])[CH3:12])[N:8]=[C:7]2[C:14]1[CH:19]=[CH:18][C:17]([O:20]C)=[CH:16][CH:15]=1.B(Br)(Br)Br.C1CCCCC=1>>[F:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH:11]([CH3:12])[CH3:13])[N:8]=[C:7]2[C:14]1[CH:15]=[CH:16][C:17]([OH:20])=[CH:18][CH:19]=1

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 69432051HCID 69432051, compound

Product 1

HCID 136358442HCID 136358442, compoundYield 75.6%

Procedure

Prepared according to Method D step C from 7-fluoro-1-isopropyl-3-(4-methoxyphenyl)-methyl-1H-indazole (0.065 g, 0.23 mmol), boron tribromide (0.10 mL, 1.05 mmol) and 0.3 mL of cyclohexene to give the product (0.047 g) as an off-white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-303c642fae69477ca8179f15072c8dc8
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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